The Main Street Hotel of Yazoo City Mississippi  / 203 S. Main Street, Yazoo City, MS 39194 /  (662)751-8886 /

 © 2013 by Main Street Hotel


  • facebook
  • Twitter Round
  • googleplus

The Main Street Hotel is located on historic Main Street in Yazoo City, Mississippi.  We are truly the place to stay in Yazoo City if you are looking for accommodations that are both fun and unique! 

Situated on the second floor, above the historic buildings of Main Street, each hotel suite features a delightful ambiance with balcony access and street view. Flat screen televisions, refrigerator, microwave, and other home away from home amenities are available upon request.

Each room at the Main Street Hotel is uniquely decorated with fine linens, antique furniture, bathrooms with claw-foot tubs and showers, and more. All rooms are non-smoking.  The balcony is accessible from all rooms through the hallway.

Facebook Page of Hotel in Yazoo City, MS.

The Main Street Hotel is proud to feature our very own reception hall.
The No Smoking Smoke House offers an unparalleled Delta experience.

Book our venue for wedding receptions, reunions, business meetings and parties.

Call us for help with information about booking your next event. 

$10 Off For AARP & AAA Members

We're Reccomended On Trip Advisor!  Click Here.

Book Direct to save!
For Reservations Call: